ALX Oncology Holdings Inc (NAS:ALXO)
$ 1.62 -0.07 (-4.14%) Market Cap: 85.44 Mil Enterprise Value: -49.60 Mil PE Ratio: 0 PB Ratio: 0.63 GF Score: 27/100
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ALX Oncology Holdings Inc at UBS Global Healthcare Virtual Conference Transcript

May 24, 2021 / 08:00PM GMT
Release Date Price: $53.9 (-1.12%)
Jaume Pons
ALX Oncology Holdings Inc. - President, CEO & Director

Good morning. My name is Jaume Pons. I am the CEO of ALX Oncology. After the usual disclaimers in Slide #1 and some picture of us in our background in Slide #2, let's move to Slide #3.

ALX Oncology is a clinical-stage immuno-oncology company that is focused in the CD47 pathway. ALX148, our Phase II clinical candidate, is a CD47 blocker that is designed to be used in combination. This design has shown in the clinic a very good tolerability profile that has enable higher dosing. And in the clinic, this higher dosing has enabled greater efficacy.

At this moment, we have clinical proof of principle, both in hematological and solid tumors. Our initial focus is on solid tumors, MDS and AML. In addition to ALX148, we have a second compound that we call SIRPalpha TRAAC that would be an IND by the end of '22.

CD47 -- in the Slide #4, CD47 as a target is highly stress in tumor cells, here on the left, in red, but it's also highly present on normal cells, in black. Therefore, if we use CD47 as a tumor associated

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